Initiation of Meiotic Recombination in Mammals
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چکیده
منابع مشابه
Initiation of Meiotic Recombination in Mammals
Meiotic recombination is initiated by the induction of programmed DNA double strand breaks (DSBs). DSB repair promotes homologous interactions and pairing and leads to the formation of crossovers (COs), which are required for the proper reductional segregation at the first meiotic division. In mammals, several hundred DSBs are generated at the beginning of meiotic prophase by the catalytic acti...
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ژورنال
عنوان ژورنال: Genes
سال: 2010
ISSN: 2073-4425
DOI: 10.3390/genes1030521